The Magical Little Capsule Liposome

By Gabrielle Lambert


There are three types of them. Multilamillar vesicles or shorter MLV, small unilamellar vesicles or SUV and LUV, or large unilamellar vesicles. They are all used for delivery of different drugs. It is usually designed as model for artificial cell, but liposome can deliver drugs in other ways as well. Their specific shape and other qualities make them very useful transferring method on numerous fields, especially in medicine. They can be inhaled as a dry powder, in form of nasal spray, hydro gel or even cream or lotion, or taken intravenously.

They can also be used in agriculture, for example. Liposomes are used as carriers for the delivery of enzymes and other nutritional supplements to foods, for example. Their usage in cosmetology is highly beneficial, because they have very high biocompatibility. They are made from the same or very similar material as the real cells. Thanks to that, different side effects are reduced, and the diffusion of active ingredients greatly improved.

It is really a tiny bubble with the membrane composed from the same, or very similar elements the cell is composed from, called phospholipids. Thanks to that, they can safely deliver their contents on the targeting area. It is very useful in cancer treatments, for example. Those little capsules can target the tumor, penetrate through its membrane and safely deliver the drug, without causing damage to surrounded tissue.

They can carry pieces of DNA, delivering genes to cells as well. They protect DNA from degrading processes and can be targeted to specific tissues. Thanks to their bi-layered membranes, they are able to carry both positively and negatively charged molecules. Bubbles can be hydrophilic or lipophilic, or have both characteristics, according to specific needs.

The method of delivering can highly affect the final drug absorbing. Various anticancer drugs will show much higher efficacy if this carrier method is used. Drug circulation is significantly prolonged, and the retention potential become much higher. Hydrolysis and drug solubility may affect the drug effectiveness, and this way this problem can be easily solved.

It is proven that different pills and capsules taken orally just lose their effectiveness due to gastric system and some other related problems. Thanks to that, the level of absorption is much lower than it should be. Liposomes are very useful for taking dietary and nutritional supplements, because they significantly improve the absorption of those nutrients, making them more effective.

Using them as the carriers for all types of dietary and nutritional supplements is much better solution. It is more effective way of delivering them to the cells and tissues. This form of transferring both lipophilic and hydrophilic nutrients within small, natural capsules bypasses the gastric system and has significantly higher level of bioavailability, as well as absorption. The drug inside those capsules is better protected, and the product is more effective.

Nano liposome is especially small variation of the same technology. Their effects are even more impressive, although there are several factors that can affect the final quality of absorption. The quality of used raw material is crucial, as well as the method of manufacturing, size and actual stability of capsules used for each particular purpose. They are the key elements for their effectiveness.




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