Lion's Mane Mushroom (Hericium erinaceus) and Nerve Regeneration

By Dr. Markho Rafael


With a unique flavor alternately described as lobster or shrimp, the gourmet mushroom Lion's Mane (Hericium erinaceus) with its out-of-this-world showy display of cascading 'teeth' also possesses singular medicinal properties - stimulating myelin and nerve regeneration (150, 151) - which upon further study may prove beneficial in a whole series of neurological conditions. Paul Stamets suggests the possible usefulness of Hericium erinaceus extract in conditions such as Alzheimer's, muscular dystrophy, M.S. and dementia. (134)

Hericium erinaceus (Lion's Mane) is known to grow in Europe, North America, Japan and China. It can be found on many broad leaf trees, from oaks, maples and sycamores to beeches and walnuts.

The active compounds that have received the most attention for their nerve regenerating properties are named erinacines, a series of low molecular weight molecules that are able to pass through the blood brain barrier - an essential attribute for any medicinal compound expected to be able to effect healing on myelin or nerve tissue. (152, 153, 154)

There are currently two Japanese patents on different extracts of Hericium erinaceus. One was filed in the 1990's for an extract named "Nerve Growth Stimulant Factor." (150, 151) The other, filed in 2004, is for a water extraction process, yielding a product that is likewise used for nerve and myelin healing. (155)

In addition to its effect on nerve regeneration, Traditional Chinese Medicine (TCM) also prescribes Hericium erinaceus extract for stomach and digestive conditions, as well as cancers of the digestive tract and related organs.

Two modern studies have confirmed this ancient wisdom. One done in 1985 showed positive results for treating atrophic gastritis. Another conducted a decade later, in 1995, showed some ameliorating effect on hepatoma, with a marked life extension of treated patients. (156)

Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Always consult a licensed medical practitioner before using any herb (or mushroom) for medicinal purposes.

Credits: Thank you, Paul Stamets, for research references.




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