Medical Information On Clodronate Liposome

By Kendra Ware


For you to know about the clodronate liposome therapy, you should know a little about cells in the body. Your liposomes are little vesicles found throughout the body that contain lipids and tiny water based areas. Macrophages are the basic cells of all immune systems in a human. The liposomes interact with macrophages to cause them to kill off intruders. They can be changed with medication to affect how the macrophage will work.

The clodronate is a drug that is classified as biophosphate. It can keep your bones from taking on a secondary cancer. Secondary cancers are those that have metastasized or spread from the original site and turned into a different kind of cancer.

When secondary cancers attack the bone, it weakens the bone structure and takes away calcium and flushes it into the blood which is called hypercalcemia. It could make confusion, nausea and being irritated easily a new way of life. The clodronate helps eliminate this by keeping the calcium levels in the blood normal.

There are two kinds of cells in bone that keeps them rebuilding in a healthy person: osteoclasts and osteoblasts. Some cancers put off a chemical that makes osteoclasts overwork themselves so that the bones become weaker. Clodronate goes directly to the areas where this activity is found in the bone.

It then attacks the cells that are infected so that they will react like healthy cells, so the cancer is unable to spread into the other healthy cells. So the bones therefore keep their calcium and can stay strong so the cancer is completely fought off instead of becoming weak and allowing the cancer to get through the permeable walls. It could mean people with bone cancers could have this treatment and see major improvements so it should be brought up with your oncologist.

The pills can be taken two times daily with no food. Administration should be at least two hours prior to or after medications and all foods including dairy products. If not followed, interference with absorption could be an issue so it is best to adhere to the recommended dosage times to keep the best blood levels.

There are side effects associated with this treatment including diarrhea, nauseousness and low calcium levels called hypocalcemia. This could make your lips or even tongue tingle but is rare for this treatment. Your kidney function could drop, and a condition called osteonecrosis has been seen. This means that the bones and tissues of the mouth and jaw get damaged and die off. To keep this from happening, your doctor will suggest a dental work up and you should care for your mouth and teeth daily, so make sure to tell your dentist you are on this medication.

Clodronate liposome treatment is known by common names your pharmacist can tell you about. Your doctor can give you a more in depth description of how they work and how long you could be on this treatment based on the severity of your case. There are some people who will not be candidates for these drugs. The pros and cons of the situation should be discussed at great length.




About the Author:



No comments:

Post a Comment